|
|
|
|
|
Figure 3-1 A simplified view of the cell-cycle control system
[ jpg]
[ tif]
|
Figure 3-2 Table of cyclin-dependent kinases that control the cell cycle
[ jpg]
[ tif]
|
Figure 3-3 Cyclin-dependent kinase structure
[ jpg]
[ tif]
|
|
|
|
|
Figure 3-4 Table of major cyclin classes involved in cell-cycle control
[ jpg]
[ tif]
|
Figure 3-5 Cyclin structure
[ jpg]
[ tif]
|
Figure 3-6 Two steps in Cdk activation
[ jpg]
[ tif]
|
|
|
|
|
Figure 3-7 Table of Cdk-activating kinases
[ jpg]
[ tif]
|
Figure 3-8 The functions of CAK in different species
[ jpg]
[ tif]
|
Figure 3-9 Table of inhibitory Cdk kinases in the Wee1 family
[ jpg]
[ tif]
|
|
|
|
|
Figure 3-10 Table of stimulatory phosphatases in the Cdc25 family
[ jpg]
[ tif]
|
Figure 3-11 Control of Cdk activity by inhibitory phosphorylation
[ jpg]
[ tif]
|
Figure 3-12 The structural basis of Cdk activation
[ jpg]
[ tif]
|
|
|
|
|
Figure 3-13 Substrate-targeting sites on cyclin–Cdk complexes
[ jpg]
[ tif]
|
Figure 3-14 Table of Cks1 proteins
[ jpg]
[ tif]
|
Figure 3-15 Table of Cdk inhibitor proteins
[ jpg]
[ tif]
|
|
|
|
|
Figure 3-16 Structure of Cdk2–cyclin A–p27
[ jpg]
[ tif]
|
Figure 3-17 Schematic of a Cdk6–INK4 complex
[ jpg]
[ tif]
|
Figure 3-18 Hyperbolic signal processing in a simple signaling system
[ jpg]
[ tif]
|
|
|
|
|
Figure 3-19 Ultrasensitivity in a signaling system
[ jpg]
[ tif]
|
Figure 3-20 Positive feedback in a signaling system can lead to a bistable system
[ jpg]
[ tif]
|
Figure 3-21 Cdk1 activation by cyclin B
[ jpg]
[ tif]
|
|
|
|
|
Figure 3-22 Assembling a Cdk1 switch at mitosis
[ jpg]
[ tif]
|
Figure 3-23 Steps in protein ubiquitination
[ jpg]
[ tif]
|
Figure 3-24 SCF is a multisubunit enzyme
[ jpg]
[ tif]
|
|
|
|
|
Figure 3-25 Table of SCF subunits in different organisms
[ jpg]
[ tif]
|
Figure 3-26 The anaphase-promoting complex (APC)
[ jpg]
[ tif]
|
Figure 3-27 Table of APC subunits in different organisms
[ jpg]
[ tif]
|
|
|
|
|
Figure 3-28 Control of late mitotic events by the APC
[ jpg]
[ tif]
|
Figure 3-29 A biochemical oscillator
[ jpg]
[ tif]
|
Figure 3-30 Assembling a Cdk oscillator
[ jpg]
[ tif]
|
|
|
|
|
Figure 3-31 Table of major gene regulatory factors controlling Cdk activity in budding yeast
[ jpg]
[ tif]
|
Figure 3-32 E2F family members and DP family members
[ jpg]
[ tif]
|
Figure 3-33 Structure of the E2F4–DP2–DNA complex
[ jpg]
[ tif]
|
|
|
|
|
Figure 3-34 Overview of the cell-cycle control system of budding yeast
[ jpg]
[ tif]
|
|
|
|