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Figure 5-1 Recognition of peptide–MHC by the T cell antigen receptor (TCR)
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Figure 5-2 Activation and effector functions of T lymphocytes
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Figure 5-3 Schematic representation of the TCR CD3 complex
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Figure 5-4 Structure of the αβ TCR heterodimer
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Figure 5-5 Schematic representation of the organization of the gene segments encoding the T cell αβ receptor for antigen
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Figure 5-6 Binding orientation of the TCR to MHC molecules
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Figure 5-7 T cell coreceptors for antigen
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Figure 5-8 Initiation of TCR signaling
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Figure 5-9 Signaling complexes formed during TCR signaling
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Figure 5-10 Regulation of Lck tyrosine kinase activity by phosphorylation and dephosphorylation
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Figure 5-11 The immunological synapse
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Figure 5-12 Activation of NFAT and AP-1 by 2+ and Erk pathways
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Figure 5-13 Activation of IL-2 transcription by signaling through the TCR and CD28
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Figure 5-14 Signaling molecules recruited by CD28
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Figure 5-15 Mechanism of entry of naïve T cells into secondary lymphoid tissue through high endothelial venules
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Figure 5-16 Naïve T lymphocyte recirculation through secondary lymphoid tissue
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Figure 5-17 Activation of naïve T lymphocytes by resident and migrant dendritic cells in secondary lymphoid tissue
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Figure 5-18 Proliferation kinetics of CD4 and CD8 T cells
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Figure 5-19 The costimulatory dialogue between CD4 T cells and dendritic cells
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Figure 5-20 Some of the second-wave costimulatory molecules induced by CD28 and CD40
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Figure 5-21 Role of CD4 T cells in the activation of CD8 T cells in secondary lymphoid tissue
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Figure 5-22 The major T H subsets that arise during differentiation of naïve CD4 T cells
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Figure 5-23 Dendritic cells integrate peripheral signals and mediate T H subset differentiation
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Figure 5-24 Table of homing molecules used by effector T lymphocytes
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Figure 5-25 T-bet induction drives the differentiation of T H1 cells
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Figure 5-26 GATA-3 induction drives the differentiation of T H2 cells
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Figure 5-27 The pleiotropic effects of IFN-γ are central to immunity mediated by T H1 cells
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Figure 5-28 Cytokines and chemokines produced by macrophages activated by T H1 cells, and their main actions
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Figure 5-29 Alternatively activated macrophages can be generated by exposure of tissue macrophages to IL-4 and/or IL-13
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Figure 5-30 Mast cell and basophil activation
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Figure 5-31 Actions of T H2 cell cytokines
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Figure 5-32 T H17 cells amplify acute immune responses mediated by neutrophils
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Figure 5-33 Effector actions of CD8 T cells
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Figure 5-34 Cytotoxic mechanisms of CD8 T cells
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Figure 5-35 Protection of cytotoxic T cells from granule contents by cathepsin B
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Figure 5-36 Death and survival signals in activated T cells
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Figure 5-37 Cytokine dependence of T cells at different stages of an immune response
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Figure 5-38 T cell activation leads to the production of effector cells and two subsets of memory cells
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