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Interviews with immunologists – Previews

Sample interviews in which leading immunologists give their perspective on key and controversial issues

View Full interviews

Relevant sections of the book are listed with each interview, and with each preview.

Polly Matzinger on detection of damage and danger  |  Ken Shortman on the nature and diversity of dendritic cells |  Gus Nossal on vaccines |  Peter Doherty on the immune response to influenza virus |  Lewis Lanier on the importance of natural killer (NK) cells |  Siamon Gordon on the many roles of macrophages - New |  Polly Matzinger on what controls different types of immune responses - New

Polly Matzinger on detection of damage and danger

Polly Matzinger
Polly Matzinger is Head of the T-Cell Tolerance and Memory Section, Laboratory of Cellular and Molecular Immunology at the US National Institutes of Health, and is well known for her provocative and sometimes controversial approach to central questions in immunology.
 

Preview – The origin of the danger theory of immunity

Relevant section – 3-0 Evolution and Function of Innate Immunity

 

Ken Shortman on the nature and diversity of dendritic cells

Ken Shortman
Ken Shortman is Head of Immunology at the Walter and Eliza Hall Institute in Melbourne where he works on the lineages and functional subsets of dendritic cells.
 

Preview – How can the same types of dendritic cells come from two different lineages?

Relevant section – 1-1 Cells of the Immune System: Differentiation in the Bone Marrow

 

Gus Nossal on vaccines

Gus Nossal
Sir Gustav Nossal is a very active Professor Emeritus at The University of Melbourne, where he pursues a long-standing interest in vaccine development after having spent 30 years as Director of The Walter and Eliza Hall Institute, internationally distinguished for its contributions to immunology.
 

Preview – The importance of adjuvants

Relevant section – 14-2 Features of successful vaccines

 

Peter Doherty on the immune response to influenza virus

Peter Doherty
Peter Doherty won the Nobel Prize in Physiology or Medicine with Rolf Zinkernagel in 1996 for the discovery that the function of MHC molecules in immunity is to present antigens to T lymphocytes. He is now a Professor at the University of Melbourne and at St Jude Children's Research Hospital in Memphis.
 

Preview – How the immune response to flu can kill

Relevant section – 10-8 Influenza Virus: Innate and Adaptive Immunity

 

Lewis Lanier on the importance of natural killer (NK) cells

Lewis Lanier
Lewis Lanier is Professor and Vice Chair, Department of Microbiology & Immunology, University of California, San Francisco where he specializes in the signaling pathways and physiological functions of natural killer cells.
 

Preview – How natural killer (NK) cells know what to attack

Relevant section – 8-1 Natural Killer Cells and their Role in Immunity

 

Siamon Gordon on the many roles of macrophages

Siamon Gordon
Siamon Gordon is GlaxoWellcome Professor of Cellular Pathology at the University of Oxford, and has devoted his research life to investigating the recognition and effector mechanisms of macrophages.
 

Preview – The activation of macrophages by interferon γ

Relevant section – 13-5 The Functions of TH1 Cells

 

Polly Matzinger on what controls different types of immune responses

Polly Matzinger
Polly Matzinger is Head of the T-Cell Tolerance and Memory Section, Laboratory of Cellular and Molecular Immunology at the US National Institutes of Health, and is well known for her provocative and sometimes controversial approach to the central questions in immunology.
 

Preview – How tissues control immune responses

Relevant section – 13-5 Delayed-Type Hypersensitivity Reactions

 





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