Figure 4-27
Examples of the best-center cluster found by Rosetta for a number of different test proteins

The level of agreement with the known native structure varies, but in many cases the overall fold is predicted well enough to be recognizable. Note, however, that the relative positions of the secondary structure elements are almost always shifted at least somewhat from their true values. Graphics kindly provided by Richard Bonneau and David Baker. (Adapted from Bonneau, R. et al.: Proteins 2001, 45(S5):119–126.)

© 1999-2007 New Science Press Ltd <info@new-science-press.com>