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Figure 3-1 The cyclin-dependent protein kinases that control progression through the cell cycle are regulated by a number of different mechanisms
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Figure 3-2 Interaction domains
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Figure 3-3 The internal structure of cells
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Figure 3-4 Mechanisms for targeting proteins
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Figure 3-5 Cathepsin D conformational switching
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Figure 3-6 Schematic representation of the mechanism by which diphtheria toxin kills a cell
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Figure 3-7 Competitive feedback inhibition
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Figure 3-8 Cooperative ligand binding
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Figure 3-9 Two models of allosteric regulation
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Figure 3-10 Ligand-induced conformational change activates aspartate transcarbamoylase
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Figure 3-11 Iron binding regulates the repressor of the diphtheria toxin gene
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Figure 3-12 Structure of the core domains of a typical GTPase and an ATPase
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Figure 3-13 Schematic diagram of the universal switch mechanism of GTPases
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Figure 3-14 The switching cycle of the GTPases involves interactions with proteins that facilitate binding of GTP and stimulation of GTPase activity
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Figure 3-15 Hypothetical model of a heterotrimeric G protein in a complex with its G-protein-coupled receptor
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Figure 3-16 The switching cycle of the elongation factor EF-Tu delivers aminoacyl-tRNAs to the ribosome
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Figure 3-17 Models for the motor actions of muscle myosin and kinesin
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Figure 3-18 Structural and functional similarity between different families of molecular switches
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Figure 3-19 The eukaryotic proteasome
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Figure 3-20 Pathway for degradation of ubiquitinated proteins
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Figure 3-21 A kinase activation cascade in an intracellular signaling pathway that regulates cell growth
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Figure 3-22 Conformational change induced by phosphorylation in glycogen phosphorylase
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Figure 3-23 Inactivation of the active site of E. coli isocitrate dehydrogenase by phosphorylation
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Figure 3-24 The conserved protein kinase catalytic domain
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Figure 3-25 Conserved mechanism of kinase activation
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Figure 3-26 Regulation of a Src-family protein kinase
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Figure 3-27 Regulation of Cdk2 activation
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Figure 3-28 The substrate-binding site of Cdk2
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Figure 3-29 Two-component signaling mechanisms
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Figure 3-30 Conserved features of RR regulatory domains
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Figure 3-31 Activation of chymotrypsinogen
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Figure 3-32 Comparison of the active sites of plasminogen and plasmin
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Figure 3-33 Schematic diagram of prepro-opiomelanocortin and its processing
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Figure 3-34 The blood coagulation cascade
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Figure 3-35 Protein splicing
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Figure 3-36 Schematic of the organization of intein-containing proteins
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Figure 3-37 Structure of an intein
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Figure 3-38 Four-step mechanism for protein splicing
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Figure 3-39 Structure of part of the Hedgehog carboxy-terminal autoprocessing domain
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Figure 3-40 Immunoglobulin A protects mucosal surfaces from pathogenic organisms
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Figure 3-41 Schematic representation of the core N-linked oligosaccharide and a representative O-linked core oligosaccharide
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Figure 3-42 Oligosaccharide processing
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Figure 3-43 The structure of Glc3Man9GlcNac2
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Figure 3-44 Membrane targeting by lipidation
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Figure 3-45 Glycosylphosphatidylinositol anchoring
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Figure 3-46 Working model for vesicular transport between Golgi compartments
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Figure 3-47 Structures of methylated arginine and lysine residues
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Figure 3-48 N-acetylation
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Figure 3-49 Sumoylation
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Figure 3-50 Cysteine nitrosylation
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